WHAT IS PEMPHIGUS?

Pemphigus vulgaris is an autoimmune disorder that involves blistering and erosion of the skin and mucous membranes. It occurs almost exclusively in middle-aged or older people. The primary lesion of pemphigus vulgaris is a soft blister filled with clear fluid that appears on healthy or irritated skin. Many cases begin with blisters in the mouth, followed by skin blisters that may come and go. The blisters inside the mouth can make it hard for the person to eat. The rupture of blisters on the skin may be painful and limit the person’s daily activities.

CAUSES

Pemphigus vulgaris is an autoimmune disorder. In the case of pemphigus vulgaris, the immune system mistakenly produces antibodies against specific proteins in the skin and mucous membranes, known as desmogleins. These proteins form the glue that keeps skin cells attached and the skin intact. When desmogleins are attacked, skin cells separate from each other and fluid can collect between the layers of skin, forming blisters that do not heal. In some cases, these blisters can cover a large area of skin.

TREATMENTS

Treatment is aimed at reducing pain and symptoms and preventing complications like infection. It involves one or more drugs and other methods. It may include any of the following: Immune-suppressing drugs, Antibiotics, Antivirals, and antifungals, Intravenous (IV) feeding, Plasmapheresis.

Make an Appointment

For appointment or any question contact us to make an appointment with Surat leading dermatologist Dr Mahendra Vaghasiya. Equipped with many years of experience in treating PEMPHIGUS patients, he will evaluate your individual skin condition and discuss the treatment options with you. You may also send an email by filling Enquiry form at https://shrihariskin.com/contact and our team will respond to your questions or appointment request as soon as possible.